--- title: Science Digest Newsletter January 2024 --- Science Digest Newsletter January 2024 | View in browser JANUARY 2024 Acetylcholinesterase inhibition in rats and humans following acute fenitrothion exposure predicted by physiologically based kinetic modeling-facilitated quantitative in vitro to in vivo extrapolation   Journal Environmental Science & Technology, Vol. 57(49) (2023), 20521–2053.   Authors Jiaqi Chen, Shensheng Zhao, Sebastiaan Wesseling, Nynke Kramer, Ivonne Rietjens, Hans Bouwmeester   Work package 5,6 Read key message Ecotoxicological evaluation of bisphenol A and alternatives: A comprehensive in silico modelling approach   Journal Journal of Xenobiotics, Vol. 13(4) (2023), 719-739.   Authors Liadys Mora Lagares, Marjan Vračko   Work package 5 Read key message Identification of the bacterial metabolite aerugine as potential trigger of human dopaminergic neurodegeneration   Journal Environment International, Vol. 180 (2023), 108229   Authors Anna-Katharina Ückert, Sina Rütschlin, Simon Gutbier, Nathalie Christine Wörz, Mahfuzur R. Miah, Airton C. Martins, Isa Hauer, Anna-Katharina Holzer, Birthe Meyburg, Ann-Kathrin Mix, Christof Hauck, Michael Aschner, Thomas Böttcher, Marcel Leist   Work package 5 Read key message A data-derived reference mixture representative of European wastewater treatment plant effluents to complement mixture assessment   Journal Environment International, Vol. 179 (2023), 108155   Authors Liza-Marie Beckers, Rolf Altenburger, Werner Brack, Beate I. Escher, Jörg Hackermüller, Enken Hassold, Gianina Illing, Martin Krauss, Janet Krüger, Paul Michaelis, Andreas Schüttler, Sarah Stevens, Wibke Busch   Work package 6 Read key message Deoxynivalenol increases pro-inflammatory cytokine secretion and reduces primary bile acid transport in an inflamed intestinal in vitro co-culture model   Journal Food Research International, Vol. 173 (Part 1) (2023), 108297   Authors Jingxuan Wang, Wouter Bakker, Laura de Haan, Hans Bouwmeester   Work package 5,6 Read key message G × E interactions as a basis for toxicological uncertainty   Journal Archives of Toxicology, Vol. 97(7) (2023), 2035–2049.   Authors Ilinca Suciu, David Pamies, Roberta Peruzzo, Petra H. Wirtz, Lena Smirnova, Giorgia Pallocca, Christof Hauck, Mark T. D. Cronin, Jan G. Hengstler, Thomas Brunner, Thomas Hartung, Ivano Amelio, Marcel Leist   Work package 6 Read key message More info on eu-parc.eu List of work packages (WPs) WP 1 Partnership management and coordination WP 2 A common science-policy-agenda WP 3 Synergies, collaborations and awareness WP 4 Monitoring and exposure WP5 Hazard assessment WP 6 Innovation in regulatory risk assessment WP 7 FAIR data WP 8 Concepts and toolboxes WP 9 Building infrastructural and human capacities The subscription service is provided by the European Environment Agency.   European Environment Agency eea.europa.eu  Kongens Nytorv 6, 1050, Copenhagen K, Denmark   You receive this email because you subscribed to PARC newsletters. Unsubscribe Manage your subscription details: PARC Sampler   PARC Science Digest   | | --- |