A tiered next-generation risk assessment framework integrating toxicokinetics and NAM-based toxicodynamics: “proof of concept” case study using pyrethroids

Journal
Archives of Toxicology, Vol. 99 (2025),  2759-2781.

Authors

Ana Fernandez-Agudo, Jose V. Tarazona

Work package
6

Journal
Environmental DNA, Vol. 7 (2025), Issue 1, e70058.

Authors
Niamh Eastwood, Arron Watson, Jiarui Zhou, Luisa Orsini

Work package
6

Evaluating the performance of multi-omics integration: a thyroid toxicity case study

Journal
Archives of Toxicology, Vol. 99 (2024), 309-332.

Authors
Sebastian Canzler, Kristin Schubert, Ulrike E. Rolle-Kampczyk, Zhipeng Wang, Stephan Schreiber, Hervé Seitz, Sophie Mockly, Hennicke Kamp, Volker Haake, Maike Huisinga, Martin von Bergen, Roland Buesen, Jörg Hackermüller

Work package
5

Investigation of peroxisome proliferator-activated receptor genes as requirements for visual startle response hyperactivity in larval zebrafish exposed to structurally similar per- and polyfluoroalkyl substances (PFAS) 

Journal
Environmental Health Perspectives, Vol. 132 (2024), Issue 7, 077007.

Authors
Sebastian Gutsfeld, Leah Wehmas, Ifeoluwa Omoyeni, Nicole Schweiger, David Leuthold, Paul Michaelis, Xia Meng Howey, Shaza Gaballah, Nadia Herold, Carolina Vogs, Carmen Wood, Luísa Bertotto, Gi-Mick Wu, Nils Klüver, Wibke Busch, Stefan Scholz, Jana Schor, Tamara Tal

Work package
5

New approach methods to assess developmental and adult neurotoxicity for regulatory use: a PARC work package 5 project

Journal
Frontiers in Toxicology, Vol. 6 (2024), 1359507.

Authors
Tamara Tal, Oddvar Myhre, Ellen Fritsche, Joëlle Rüegg, Kai Craenen, Kiara Aiello-Holden, Caroline Agrillo, Patrick J. Babin, Beate I. Escher, Hubert Dirven, Kati Hellsten, Kristine Dolva, Ellen Hessel, Harm J. Heusinkveld, Yavor Hadzhiev, Selma Hurem, Karolina Jagiello, Beata Judzinska, Nils Klüver, Anja Knoll-Gellida, Britta A. Kühne, Marcel Leist, Malene Lislien, Jan L. Lyche, Ferenc Müller, John K. Colbourne, Winfried Neuhaus, Giorgia Pallocca, Bettina Seeger, Ilka Scharkin, Stefan Scholz, Ola Spjuth, Monica Torres-Ruiz, Kristina Bartmann

Work package
5

Water quality monitoring with the multiplexed assay MitoOxTox for mitochondrial toxicity, oxidative stress response and cytotoxicity in AREc32 cells

Journal
Environmental Science & Technology, Vol. 58 (2024), Issue 13, 5716-5726.

Authors
Jungeun Lee, Maria König, Georg Braun, Beate I. Escher

Work package
5